OUR CAPABILITY

Transforming our ability to understand and manage our environment through world-leading science.

NEOF PILOT COMPETITIONS

Test adventurous genomic, metabolomic and proteomic ideas and generate pilot data to support applications for larger-scale studies.

The 2024 Early Career Researchers pilot round has closed. Successful applicants have been notified and will need to submit their samples by 2nd December 2024.

The 2024 Independent round for Genomics, Metabolomics and Proteomics pilot projects deadline is 1st July. Applicants will need to have consulted between 16/05 and 06/06.

New generation sequencing

We provide the latest Illumina and Pacific Biosciences platforms for applications including population genomics, transcriptomics and de novo sequence assembly. This capability allows users to generate a reference genome for their study organism which then unlocks the latest genomic methods to examine genome wide genetic diversity through resequencing, the response of its genes to the environment through RNAseq, epigenetic programming using methylation analysis and much more.

Isoform analysis

We provide full-length analysis of transcripts to understand the diversity of different splice variants produced by a gene, to support characterisation of proteomic diversity and to annotate de novo genomes.

Epigenomics

We provide methylation analysis to understand epigenetic modifications of the genome and its consequences for gene expression, development and phenotype.

Quantitative proteomics

We offer a wide range of mass-spec instrumentation for accurate and sensitive quantification to protein signatures to discover differences between treatments and, coupled with genomics, can support analyses with de novo genomes and transcriptomes. Read more about Proteomics at NEOF: NEOF Proteomics FAQs, Case Studies.

Quantitative metabolomics

We offer GC and LC mass spectrometry, as well as vibrational spectroscopy, to analyse metabolites and other small molecules at high sensitivity and specificity from environmental mixtures. Read more about Metabolomics at NEOF; Case Studies.

Phenomics and meta’omics

We offer access to a range of imaging technologies for the automated phenotyping of biological samples. We have large scale scanners for multispectral imaging (450–1000 nm) and quantitative analysis of chlorophyll fluorescence from plants. Bench top versions of both are available for protocol development. We also offer access to expertise in 3-D imaging, in the analysis (including comparative analysis) of morphometric datasets, and in linking phenotypes, including metabolomic and proteomic data, to genotypic data.

Single-cell omics

We provide capability in single-cell transcriptomics, proteomics and RAMAN spectroscopy to analyse the heterogeneity among cell populations from environmental communities or from within an individual.

CONTACT US

Empowering the next generation of environmental researchers.

If you would like more information about NEOF and the services we offer, or make any other enquiry, please complete our form.